Who says we have to suffer...to live a healthy happy vibrant life?
Red wine and dark chocolate... might seem decadent...but these guilty pleasures also might help us live longer...and healthier lives. Red wine and dark chocolate definitely improve an evening..but they also contain resveratrol..which lowers blood sugar. Red wine is a great source of catechins..which boost protective HDL cholesterol. Green tea? Protects your brain..helps you live longer..and soothes your spirit.
Red Wine, Green Tea and Dark Chocolate, the blog, is about living the good life...a life we create with our thoughts and our choices...and having fun the whole while!
I say lets make the thoughts good ones..and let the choices be healthy...exciting...and delicious! Bon Appetit!
Monday, April 20, 2020
Monday, April 13, 2020
, (4), 988; https://doi.org/10.3390/nu12040988
Abstract: The world is in the grip of the COVID-19 pandemic. Public health measures that can reduce the risk of infection and death in addition to quarantines are desperately needed. This article reviews the roles of vitamin D in reducing the risk of respiratory tract infections, knowledge about the epidemiology of influenza and COVID-19, and how vitamin D supplementation might be a useful measure to reduce risk. Through several mechanisms, vitamin D can reduce risk of infections. Those mechanisms include inducing cathelicidins and defensins that can lower viral replication rates and reducing concentrations of pro-inflammatory cytokines that produce the inflammation that injures the lining of the lungs, leading to pneumonia, as well as increasing concentrations of anti-inflammatory cytokines. Several observational studies and clinical trials reported that vitamin D supplementation reduced the risk of influenza, whereas others did not. Evidence supporting the role of vitamin D in reducing risk of COVID-19 includes that the outbreak occurred in winter, a time when 25-hydroxyvitamin D (25(OH)D) concentrations are lowest; that the number of cases in the Southern Hemisphere near the end of summer are low; that vitamin D deficiency has been found to contribute to acute respiratory distress syndrome; and that case-fatality rates increase with age and with chronic disease comorbidity, both of which are associated with lower 25(OH)D concentration. To reduce the risk of infection, it is recommended that people at risk of influenza and/or COVID-19 consider taking 10,000 IU/d of vitamin D3 for a few weeks to rapidly raise 25(OH)D concentrations, followed by 5000 IU/d. The goal should be to raise 25(OH)D concentrations above 40–60 ng/mL (100–150 nmol/L). For treatment of people who become infected with COVID-19, higher vitamin D3 doses might be useful. Randomized controlled trials and large population studies should be conducted to evaluate these recommendations.
Friday, February 1, 2019
Monday, November 12, 2018
Thursday, May 31, 2018
Several risk factors for Vitamin C deficiency have been identified, including disease, smoking, and inadequate dietary intake, but also pregnancy and genetics have been shown to affect Vitamin C levels. Based on Vitamin C’s involvement in important processes in the brain, there is reason to believe that these could be adversely affected by a deficiency. The functions of Vitamin C include its antioxidant function of upholding redox balance, and thus reducing the effects of oxidative stress in the brain. But vitamin C also has other important functions in the brain. These include modulation of the cholinergic, catecholinergic, and glutamergic systems of the brain. Vitamin C supports the general development of neurons ( nerve cells in the brain) through maturation, differentiation and myelin formation. Vitamin C is involved in several processes in the vascular system including helping maintain integrity and function of blood vessels, e.g., nitric oxide synthase, which regulates vessel relaxation through production of nitric oxide.
Vitamin C deficiency appears to pose numerous threats to cognitive function. The involvement of vitamin C in vessel integrity, antioxidant balance and neuromodulation in the brain has prompted investigations into the effect of the vitamin on the developing brain, in aging and in stroke. In the developing brain, neuronal density and maturation is compromised by Vitamin C deficiency, giving rise to decreased brain volume. In the aging brain deficiency affects ACh release and may impair cognitive function through reduced signal transduction but also through amyloid β deposition resulting in generation of reactive oxygen species and increased neuronal impairment in people suffering from Alzheimer’s disease. In stroke, Vitamin C deficiency may result in decreased vessel integrity through decreased nitric oxide synthase generation and impaired synthesis of mature collagen; potentially leading to increased plaque formation and incidence of stroke. Furthermore, an increase in infarct area may result from oxidative damage causing increased neuronal death.