Sugary Drinks Linked to High Death Tolls Worldwide

Consumption of sugary drinks may lead to an estimated 184,000 adult deaths each year worldwide, according to research published today in the journal Circulation and previously presented as an abstract at the American Heart Association Council on Epidemiology and Prevention in 2013.

“Many countries in the world have a significant number of deaths occurring from a single dietary factor, sugar-sweetened beverages. It should be a global priority to substantially reduce or eliminate sugar-sweetened beverages from the diet,” said Dariush Mozaffarian, M.D., Dr.P.H., senior author of the study and dean of the Friedman School of Nutrition Science & Policy at Tufts University in Boston.

In the first detailed global report on the impact of sugar-sweetened beverages, researchers estimated deaths and disabilities from diabetes, heart disease, and cancers in 2010. In this analysis, sugar sweetened beverages were defined as any sugar- sweetened sodas, fruit drinks, sports/energy drinks, sweetened iced teas, or homemade sugary drinks such as frescas, that contained at least 50 kcal per 8oz serving. 100 percent fruit juice was excluded.

Estimates of consumption were made from 62 dietary surveys including 611,971 individuals conducted between 1980 and 2010 across 51 countries, along with data on national availability of sugar in 187 countries and other information. This allowed capture of geographical, gender and age variation in consumption levels of sugar- sweetened beverages in different populations. Based on meta-analyses of other published evidence on health harms of sugar-sweetened beverages, the investigators calculated the direct impact on diabetes and the obesity-related effects on cardiovascular disease, diabetes and cancer.

In 2010, the researchers estimate that sugar-sweetened beverages consumption may have been responsible for approximately:

133,000 deaths from diabetes
 

45,000 deaths from cardiovascular disease

6,450 deaths from cancer

“Some population dietary changes, such as increasing fruits and vegetables, can be challenging due to agriculture, costs, storage, and other complexities. This is not complicated. There are no health benefits from sugar-sweetened beverages, and the potential impact of reducing consumption is saving tens of thousands of deaths each year,” Mozaffarian said.

Overall, in younger adults, the percent of chronic disease attributed to sugar-sweetened beverages was higher than the percent in older adults.

The health impact of sugar-sweetened beverage intake on the young is important because younger adults form a large sector of the workforce in many countries, so the economic impact of sugar-sweetened beverage-related deaths and disability in this age group can be significant. It also raises concerns about the future. If these young people continue to consume high levels as they age, the effects of high consumption will be compounded by the effects of aging, leading to even higher death and disability rates from heart disease and diabetes than we are seeing now.

Singh GM, Micha R, Khatibzadek S, Lim S, Ezzati M, and Mozaffarian, D. “Estimated global, regional, and national disease burdens related to sugar-sweetened beverage consumption in 2010.” Circulation. Published online ahead of print 06-29-15. doi:10.1161/CIRCULATIONAHA.114.010636

Sugary beverages start to wreck your health in just two weeks.

Still drinking soft drinks or sugar sweetened beverages? It is time to stop. A new study shows us what just two weeks of drinking soda can do to your heart. And the subjects were young healthy people.

Sugary drinks have been linked to obesity, heart disease, high blood pressure and diabetes. What is worse, the more soda (or sweet tea, or lattes) people drink the more likely these outcomes. The sugar industry and soft drink companies argue that association isn’t proof that one actually causes the other. But you have to agree that when population studies show a link again and again, and the mechanism of harm is plausible, it is silly to deny such strong evidence.

This is exactly how how we proved smoking cigarettes caused disease. But when it comes to discovering the effects on a habit on our health there’s nothing like controlled experiments. And the best evidence to prove cause and effect comes from double blind placebo controlled studies.

And when you’re studying heart disease, all the study has to do is look at changes in markers of heart disease risk, such as LDL cholesterol, apoB, triglycerides and uric acid in the blood.

A new study did just that. The study has been published online ahead of print in the American Journal of Clinical Nutrition. The researchers recruited a group of 85 people aged 18-40, and divided them into 4 groups. For 2 weeks participants drank beverages sweetened with high-fructose corn syrup (HFCS) making up 0 percent, 10 percent, 17.5 percent or 25 percent of their daily caloric requirement. The participants were blinded to their drink content, and in order to do that the 0-percent drink for the control group was sweetened with aspartame.

Within 2 weeks, the people who were on the HFCS drinks had higher levels of LDL, triglycerides and uric acid, and the higher the HFCS they drank, the higher the level of heart risk factors.

Although the American Heart Association and the World Health Organization recommend that people limit added sugar to no more that 5 percent of daily calories, very few people do so, and levels of added sugar in the 10-20 percent are typical of the American diet. By this study’s assessment, the average American person’s sugar intake is certainly enough to increase cardiac risk.

Would replacing HFCS with regular sugar (sucrose) make a difference? Not likely. The fructose content in table sugar is 50 percent, compared to 55 percent in HFCS – just a slight difference – and since fructose is metabolized in our body in a way that promotes fat production, raises triglycerides and affects cholesterol levels, either one of these sweeteners would probably have the same negative effects; there's no reason to assume that sugar is any more safe than HFCS.

Study: Soda and Sugar Drive Obesity

New research powerfully implicates soda and other sugary drinks as culprits in the obesity epidemic.

A huge, decades-long study involving more than 33,000 Americans has yielded the first clear proof that drinking sugary beverages interacts with genes that affect weight, amplifying a person’s risk of obesity beyond what it would be from heredity alone.

This means that such drinks are especially harmful to people with genes that predispose them to weight gain. And most of us have at least some of these genes.

In addition, two other major experiments have found that giving children and teens calorie-free alternatives to the sugary drinks they usually consume leads to less weight gain.

Collectively, the results strongly suggest that sugary drinks cause people to pack on the pounds, independent of other unhealthy behavior such as overeating and getting too little exercise, scientists say.

That adds weight to the push for taxes, portion limits like the one just adopted in New York City, and other policies to curb consumption of soda, juice drinks and sports beverages sweetened with sugar.

Soda lovers do get some good news: Sugar-free drinks did not raise the risk of obesity in these studies.

“You may be able to fool the taste” and satisfy a sweet tooth without paying a price in weight, said an obesity researcher with no role in the studies, Rudy Leibel of Columbia University.

The studies were being presented Friday at an obesity conference in San Antonio and were published online by the New England Journal of Medicine.

The gene research in particular fills a major gap in what we know about obesity. It was a huge undertaking, involving three long-running studies that separately and collectively reached the same conclusions. It shows how behavior combines with heredity to affect how fat we become.

Having many of these genes does not guarantee people will become obese, but if they drink a lot of sugary beverages, “they fulfill that fate,” said an expert with no role in the research, Jules Hirsch of Rockefeller University in New York. “The sweet drinking and the fatness are going together, and it’s more evident in the genetic predisposition people.”

Sugary drinks are the single biggest source of calories in the American diet, and they are increasingly blamed for the fact that a third of U.S. children and teens and more than two-thirds of adults are obese or overweight.

Consumption of sugary drinks and obesity rates have risen in tandem —both have more than doubled since the 1970s in the U.S.

In one study, researchers randomly assigned 224 overweight or obese high schoolers in the Boston area to receive shipments every two weeks of either the sugary drinks they usually consumed or sugar-free alternatives, including bottled water. No efforts were made to change the youngsters’ exercise habits or give nutrition advice, and the kids knew what type of beverages they were getting.

After one year, the sugar-free group weighed more than 4 pounds less on average than those who kept drinking sugary beverages.

“I know of no other single food product whose elimination can produce this degree of weight change,” said the study’s leader, Dr. David Ludwig of Boston Children’s Hospital and the Harvard School of Public Health.

The weight difference between the two groups narrowed to 2 pounds in the second year of the study, when drinks were no longer being provided. That showed at least some lasting beneficial effect on kids’ habits. The study was funded mostly by government grants.

A second study involved 641 normal-weight children ages 4 to 12 in the Netherlands who regularly drank sugar-sweetened beverages. They were randomly assigned to get either a sugary drink or a sugar-free one during morning break at their schools, and were not told what kind they were given.

The studies “provide strong impetus” for policies urged by the Institute of Medicine, the American Heart Association and others to limit sugary drink consumption.

The genetic research was part of a much larger set of health studies that have gone on for decades across the U.S., led by the Harvard School of Public Health.

Researchers checked for 32 gene variants that have previously been tied to weight. Because we inherit two copies of each gene, everyone has 64 opportunities for these risk genes. The study participants had 29 on average.

Every four years, these people answered detailed surveys about their eating and drinking habits as well as things like smoking and exercise. Researchers analyzed these over several decades.

A clear pattern emerged: The more sugary drinks someone consumed, the greater the impact of the genes on the person’s weight and risk of becoming obese.

For every 10 risk genes someone had, the risk of obesity rose in proportion to how many sweet drinks the person regularly consumed. Overall calorie intake and lifestyle factors such as exercise did not account for the differences researchers saw.

This means that people with genes that predispose them to be obese are more susceptible to the harmful effects of sugary drinks on their weight, said one of the study leaders, Harvard’s Dr. Frank Hu. The opposite also was true — avoiding these drinks can minimize the effect of obesity genes.

“Two bad things can act together and their combined effects are even greater than either effect alone,” Hu said. “The flip side of this is everyone has some genetic risk of obesity, but the genetic effects can be offset by healthier beverage choices. It’s certainly not our destiny” to be fat, even if we carry genes that raise this risk.

High Carb Diet Bad For Elderly Cognitive Function

Just say no!

Seniors who follow a high-carbohydrate diet are nearly four times as likely to develop mild cognitive impairment, especially if their food intake is high in sugar, researchers from the Mayo Clinic report in the Journal of Alzheimer's Disease. They also found that seniors whose diets are high in protein and fat are less likely to develop cognitive impairment.

The researchers found that:

      

    The highest carbohydrate eaters had a 1.9 times higher risk of mild cognitive impairment than the participants who ate the fewest carbs.

             

   The highest sugar consumers had a 1.5 times higher risk of cognitive impairment compared to the lowest consumers.           

    

   The participants with the highest fat intake had a 42% lower risk of developing cognitive impairment compared to the lowest fat eaters.

            

   The highest protein consumers had a 21% lower chance of developing dementia compared to the lowest consumers of protein.

      

   When taking into account fat and protein intake, the highest carb eaters had a 3.6 times higher chance of developing mild cognitive impairment.

"Relative Intake of Macronutrients Impacts Risk of Mild Cognitive Impairment or Dementia"
Rosebud O. Roberts et al
Journal of Alzheimer's Disease, October 2012. 10.3233/JAD-2012-120862

Sugary beverages linked to increased heart risk in men.

Throw out the sugar packets, skip the sweet tea, and just say no to sugar sweetened soft drinks...if you want to do everything you can to keep your heart healthy. So say the results of a new Harvard study.

Just one sugar-sweetened drink a day may be enough to raise a man’s risk for heart disease, a new study suggests.

Men who drank just one sugary drink a day had a 20% higher risk of heart disease than did non-drinkers, says researcher Frank Hu, MD, PhD, professor of nutrition and epidemiology at the Harvard School of Public Health.

"This study provides strong evidence that higher consumption of sugary beverages is an important risk factor for heart disease," he says. "Even moderate consumption -- one soda per day -- is associated with a 20% increased risk."

Hu's team followed nearly 43,000 men in the Health Professionals Follow-up Study. Previously, they conducted a similar study with women enrolled in the Nurses' Health Study. In that study, they also found a link between sugar-sweetened drinks and heart disease.

"In this one we tried to replicate the results in men," he tells WebMD. The results are very consistent, he says. "That is really enhancing the validity of the findings."

The team found a link, but that does not prove cause and effect. The study is published in the journal Circulation.

Naturally, the Sugar Association, an industry group, took exception with the findings, stressing that sugar is not the main culprit, but lifestyle. So did the American Beverage Association. 

Men who drank sugar-sweetened drinks daily had higher indicators for heart disease than the non-drinkers did.

Those who had a daily sugar-sweetened drink had higher levels of blood fats called triglycerides, a risk factor for heart disease. They had lower levels of HDL or "good"cholesterol, another risk factor.

American Heart Association (2012, March 12). Sugar-sweetened drinks linked to increased risk of heart disease in men. ScienceDaily. Retrieved March 13, 2012, from http://www.sciencedaily.com­/releases/2012/03/120312162744.htm