Methylation – the addition of a methyl group (CH4 – one carbon attached to three hydrogens) to another molecule – is an essential and vital biochemical process within the human body that is involved in a large number of biochemical pathways involving neurotransmitters, detoxification, cardiovascular health, eye health, muscle health, bone health, and redox ( antioxidant) balance. A number of specific nutrients are necessary for methylation to occur normally.
Methylation depends on you having methyl donors on board. Methylcobalamin is a form of vitamin B-12 that is a methyl donor. Methyl folate is a a form of folic acid that also supports methylation. Pyridoxyl 5 phosphate is an active form of vitamin B-6 that contributes to this precess as well. Other methyl donors include trimethylglycine and N Acetyl Cysteine.
Now scientists at the University of York have discovered that very small chemical changes to dietary flavonoids cause very large effects when the plant natural products are tested for their impact on the human immune system.