Who says we have to suffer...to live a healthy happy vibrant life?

Red wine and dark chocolate... might seem decadent...but these guilty pleasures also might help us live longer...and healthier lives. Red wine and dark chocolate definitely improve an evening..but they also contain resveratrol..which lowers blood sugar. Red wine is a great source of catechins..which boost protective HDL cholesterol. Green tea? Protects your brain..helps you live longer..and soothes your spirit.

Food for Thought, the blog, is about living the good life...a life we create with our thoughts and our choices...and having fun the whole while!

I say lets make the thoughts good ones..and let the choices be healthy...exciting...and delicious! Bon Appetit!

Thursday, September 22, 2011

Poor Glucose Control Raises Risk of Dementia and Alzheimer's

Getting your blood sugar under control appears to have far reaching effects according to a new study coming out of Japan. The study links glucose regulation with dementia and prediabetes and diabetes with dementia, vascular dementia and Alzheimer’s Disease. In the population group studied poor glucose control accounted for one in six cases of dementia and one in five cases of Alzheimer’s.

Diabetes patients were 74% more likely to develop dementia of any type over 15 years of follow-up after adjustment for other confounding factors.

And Alzheimer's disease developed 2.05-fold more often in those with diabetes than in those with normal glucose tolerance.
Most interesting, though, was the strong risk prediction of postload glucose levels during the oral glucose tolerance test, mimicking how meals are metabolized.

Higher two-hour postload glucose levels correlated with greater risk of developing dementia, Alzheimer's disease, and vascular dementia.
After adjustment for age, sex, hypertension, electrocardiogram abnormalities, body mass index, waist-to-hip ratio, total cholesterol, prior stroke, education, smoking, alcohol intake, and physical activity in the multivariate analysis:
Two-hour postload glucose levels of 7.8 to 11.0 mmol/L predicted 50% elevated risk of all-cause dementia and 87% elevated likelihood of Alzheimer's disease.

Two-hour postload glucose levels above 11.0 mmol/L predicted 2.47-fold higher risk of all-cause dementia and 3.42-fold elevated Alzheimer's risk and 2.66-fold elevated vascular dementia risk (P=0.01).

Those findings suggested "that postprandial glucose regulation is critical to prevent future dementia.

Hyperglycemia itself may have an impact on the brain through atherosclerosis, oxidative stress and accumulation of advanced protein glycation, and changes in insulin metabolism yielding distorted amyloid metabolism.

One important tool to reduce high after meal blood sugar levels is the glycemic index. Foods that are low are better than foods that are high.
Have a look at how the foods you eat frequently score on the index here.

Ohara T, et al "Glucose tolerance status and risk of dementia in the community: The Hisayama Study" Neurology 2011; 77: 1126–1134.

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